These are some of the prominent waterways in the Steelhead Alley region where anglers can target steelhead and other species during various seasons. Keep in mind that there may be other smaller tributaries and streams in the area that also offer fishing opportunities.
| Waterway | State |
| Walnut Creek | Pennsylvania |
| Elk Creek | Pennsylvania |
| Rocky River | Ohio |
| Conneaut Creek | Pennsylvania & Ohio |
| Grand River | Ohio |
| Vermilion River | Ohio |
| Black River | Ohio |
| Huron River | Ohio |
| Cattaraugus Creek | New York |
| Eighteen Mile Creek | New York |
| Twenty Mile Creek | Pennsylvania |
| Sixteen Mile Creek | Pennsylvania |
| Crooked Creek | Pennsylvania |
| Chagrin River | Ohio |